CERVICAL CANCER

The United States Food and products Administration (FDA) approved Digene's cervical cancer detection tests as a combination of detection of cervical cancer screening tool, it is the 50 years of history after another Pap smear has the same value of the means of inspection. FDA approval in 30 women over the age of the use of cervical cytology and the cause of human papillomavirus (Hybrid Capture test) combination of screening methods.

The survey data shows that China's young age at sexual maturity widespread than the'70s ahead by 4 ~ 5-year-old, 21-year-old youth, 79% have had premarital sex, in rural areas more than 80%, premarital sex showing a younger age trends. Chinese Academy of Medical Sciences Institute of Cancer Epidemiology Research Director Dr Lam Qiao You have three years before proposing any more sex or over the age of 21 have sex with women should start regular screening for cervical cancer, 65-year-old felt very low risk of cervical cancer, is generally not in favor of women over the age of 65 into the OK cervical cancer screening.

According to history and clinical performance, especially with bleeding, should first think of a possible cervical cancer, should do a detailed body check and gynecological examinations, and the following examinations:

(1) scratch cervical cytology screening is found early cervical lesions and early cervical cancer main methods. But attention to the correct location and examination material carefully, 5% ~ 10% false negative rate, it should be combined with clinical, and periodic examinations, screening for this method.

(1) tumor marker

A Prevention:

Prevention is a cause of prevention, the goal is to prevent the occurrence of cancer, whose mandate includes the study of cancer etiology and risk factors for the chemical, physical, biological, and other specific carcinogenic, in vitro and in vivo tumor promoter pathogenic factors and conditions, to take precautionary measures against health and the body, picking <BR> admission to strengthen environmental protection, appropriate diet, suitable for sports, to promote physical and mental health. This is a more difficult long-term task. Cervical cancer is not entirely clear cause, but known to many factors and their closely related to these factors can be controlled, such as promoting later marriage, early marriage and sex life ban disorder, family planning, strengthen sexual morality and sexual health education, active in the prevention and treatment of cervical cancer and other diseases.

(1) tumor marker
1. Cervical cancer associated antigen (TA-4) and squamous cell carcinoma-related surprise move (SCC) by RIA of the patients with serum values TA-4, found 61% of the patients with positive TA-4, level 5 μ g / L or more. TA-4 SCC is the Asian ingredients, cervical cancer is the special markings. Early cervical cancer TA-4 with a marked increase in SCC can be used to predict the therapeutic effect in patients with cervical cancer and whether there are any recurrence.
2. Serum tumor-associated antigen (CA-125) in patients with cervical cancer serum CA-125 may be increased. Determination of patients with SCC and CA-125; Rose found SCC, squamous cell carcinoma of 67%, adenocarcinoma of 2.5 per thousand; CA-125 increase, squamous cell carcinoma was 26%, 75% adenocarcinoma. Therefore CA-125 can be used as a sign of cervical cancer.
3. Urine promote clips of gonadotropin (UGF) not normal mmmol / L, early cervical cancer patients positive rate of 26 per 1,000, Advanced positive rate was 67%. UGF during treatment of patients with SCC and the disease can be as dynamic observation of the signs.
4. Antigen (CEA) in patients with gynecologic malignancies 60% positive results (≥ 5 μ g / L), which was 38% of cervical carcinoma in situ and invasive carcinoma of cervical cancer was 57%. CEA and tumor stage of a certain relationship, but also of surgery and chemotherapy this effect. As surgery thorough, two weeks after the CEA to negative, as surgery is not completely or relapse, or continuing high level of CEA increased; If chemotherapy effective, CEA rapidly decreased to normal, on the contrary it increased or did not change.
(2), gynecological examinations <BR> Unless general gynecological examination requirements like genital examination, overcast gleaned for a check-up and inspection, the inspection must do triple up. Checks should pay attention to the latter part of pelvic examination and pelvic conditions.
(3), histopathological examination
1. Colposcopy exfoliated cells smears early diagnosis of cervical cancer screening rate was about 90%. To enhance the positive rate, cervical cancer should be a good site, with the squamous epithelium of the junction of epithelial biopsy smears, older women scales, column skin junction to the extension of the neck when the shift, in addition to the cervical, vaginal smears from the Department should take from cervical smears, to avoid misdiagnosis. Cervical blowing tablets of small feet or small biopsy of the tongue.
Jiang abnormal vaginal shedding non-cells are abnormal cervical cancer caused many factors, in addition to parts of the female genital cancer, inflammation of the vagina can cause. Therefore, if found abnormal Pap smear cells, for further examination.
2. Cervical living tissues of the cervix and curettage of cervical screening by cervical biopsy is the biopsy forceps on the folder from the cervix organizations sent pathological examination, the diagnosis of cervical cancer is the most reliable method. The above results can be positive or Ying cases, or cervical lesions and cervical cancer identification difficult, as should cervical biopsy.
(4) iodine test <BR> iodine solution will be manufactured in cervical smear and vaginal mucosa, Iodine staining of the situation. Coloring were not as positive in the biopsy site. When cells cervical smear abnormalities or clinical cancer can Ying colposcopy, and without the help of iodine can be found in abnormal positions. The iodine solution used two First Schiller solution, the other is Lugol solution, the solution concentration is 10 times greater than the former, fast staining.
(5) fluorescence inspection <BR> luciferase tumor and the role of parents, to patients with oral or intravenous injection, cancer tissue than in normal tissue absorb more often, cervical cancer can be diagnosed early.
1. UV fluorescence excitation of oral examination showed normal cervical purple, cervical erosion performance for the Purple brown, cancer or precancerous lesions showed yellow (positive).
2. Helium - Cd laser fluorescence spectroscopy cervical cancer and cervicitis spectral curve with the shape of the difference between the peak wavelength, half-width and area ratio is different. Early diagnosis rate of about 90%.

Beijing - China news agency: Beijing Union Medical College Hospital professor of obstetrics and gynecology, director of King Lang and disclosed today that China has nearly 100,000 women each year from cervical cancer, in 2001 about 20,000 women died of cervical cancer, and the present new detection method has been to fight the disease become possible. He therefore appealed to women actively involved in cervical cancer screening.

As the Chinese head of gynecologic endoscopy, cervical lesions in collaboration Lang, head of the King and in a news briefing held here announced: cervical cancer screening technology has made breakthrough progress in the newly developed second generation detection technology can detect 13 kinds of high-risk HPV, thus making detection cervical high cervical lesions and the sensitivity increased to 95%.

Cervical cancer is one of the common gynecologic malignancies, the incidence of cancer in women ranked second only to breast cancer. Worldwide annual new cases of cervical cancer are 466,000. According to statistics, China's annual new cases of cervical cancer a few more than 130,000 annual deaths from cervical cancer of about 50,000 people, or women, a cancer mortality. As the current threats to the health of women, "Hongyan killers," one of cervical cancer in recent years more and more medical experts and patients concerns
. Reporters interviewed on the issue of kids Geng, director of obstetrics and gynecology physicians.

According to the latest issue of "Journal of the National Cancer Institute" (Journal of the National Cancer Institute), a report said the detection of human papilloma virus (HPV) may help identify potential cervical cancer patients.

Belgian researchers examined 15 of the participants in meaningful unknown atypical squamous cells (ASCUS) women information, they concluded that the first results of suspicious Pap smear, HPV testing than OK again Pap smear screening can more accurately predict whether the patient is likely to develop into Palace cervical cancer.

Cervical cancer in women is the world's second largest after the common breast cancer. China's new cases each year about 131,500 of the world's total number of new cases of cervical cancer in 28.8%. From 1990 to 1992, China's mortality rate was 3.25/10 10,000 cervical cancer, cancer death in women in the composition of 4.86%, ranking sixth.
Chairman of the China Cancer Research Foundation PENG Yu-disclosed to the press, cervical cancer preventive vaccine research has made significant progress, experts expect that the vaccine will be in two to three years listed.