Pathologic classification of cervical cancer

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One, cervical intraepithelial neoplasia lesions

(1) cervical dysplasia
Mild dysplasia, cell atypia lighter, cell disorder with slightly; Obviously, moderate atypia, cell arrangement disorder; Severe significant abnormal cell polarity almost disappeared, and difficult to distinguish carcinoma in situ.

(2) cervical carcinoma in situ
Also known as epithelial carcinoma. Lesions to the cortex, basal membrane of penetration, mesenchymal no infiltration. Abnormal cells along the cervical glandular cavity openings in the transitional zone cervical glands, resulting in the original column gland cells for multiple abnormal squamous cells alternative, but still maintain integrity of the basement membrane gland, known as cervical carcinoma in situ involving glands.

2, invasive carcinoma cervix

(1) squamous cell carcinoma
About 90% to 95%. Squamous cell carcinoma and adenocarcinoma in appearance without special differences, the two are in the Department of vaginal or cervical carotid tube.

1. Giant seized cervical intraepithelial neoplasia lesions and early invasive carcinoma and under very early invasive carcinoma cervix, the naked eye observation no obvious abnormality, or similar cervical erosion, with the progressive development of the disease, has the following four types:
Exogenous (1): the most common. Lesions outward growth, also known as cauliflower-textured cauliflower. Organizations crisp, initially for the polyp-like papillary or uplift, and then to the development of vaginal prominent ranging from the size of the cauliflower-like vegetation, breach of easy bleeding.
(2) of the type: carcinoma of the cervix deep tissue infiltration, and the expansion of the uterine cervix under paragraph. Cervical mast while the hard, smooth surface and slight erosion, swelling of cervical cancer as a whole barrel.
3. Ulcer type: the two foci of the continued development of cancer tissue necrosis depression formed off ulcer or empty-shaped fiery Yamaguchi.
(4) type of neck: cervical cancer in the mouth, concealed in cervical, uterine cervix and into the next layer of blood and transferred to the pelvic lymph nodes, unlike endogenous type, which is special to the proliferation of invasive cervical and uterine segment of the blood and transferred to the pelvic lymph nodes, unlike Endogenous type, which is special to the proliferation of invasive cervical canal.

2. Microscopy

Under early invasive carcinoma (1): endoscopic see measurable lesions, interstitial infiltration of not more than five inches deep, horizontal spread of not more than seven inches, tumor infiltration by small lesions integration of different tumor cell differentiation.
(2) cervical invasive carcinoma: that mesenchymal tumor invasion has exceeded the scope of measurable early invasive carcinoma, or mesh with the massive integration Baptist mesenchymal weep. According to the generation of cells, generally fall into three: Level 1: better differentiation, cancer nests are in the majority were like keratosis, cancer-Visibility. Level II: moderate differentiation, the middle of cervical epithelial cell differentiation, cell sizes, cancer nest keratosis no obvious phenomenon. Ⅲ: mostly small cell undifferentiated (equivalent to the underlying cervical intraepithelial neoplasia undifferentiated cells).

(2) adenocarcinoma accounts for approximately 5% to 10%.
1. Giant seized from the cervix, cervical wall infiltration. When the tumor longer than that process to a certain extent, I cervix, pregnancy often violated organizations. May was papillary cancer, bud-shaped, and supervising soup or infiltration. If the focus inward growth, cervical appearance can be completely normal, but parts of the cervical neck swelling like barrel.

2. Microscopy
Mucinous adenocarcinoma (1): The most common, from cervical mucus columnar cells, glandular structure microscope, cells containing mucus.
Cervical malignant adenomas (2): also known as the minimum deviation adenocarcinoma. Seemingly benign tumor cells, often invasive cervical wall deep.
3. Squamous carcinoma: cervical mucosa from columnar cells, and less see, naive cancer, adenocarcinoma and squamous cell carcinoma at the same time to develop in the direction of the father

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Tags: bleeding, carcinoma, cell, early, erosion, lesions, lymph, nodes, spread, vaginal

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