Cervical cancer cure of electron beam radiotherapy good effect

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Spain Martinez-Monge, physicians, a recent study showed that the limitations and advanced cervical cancer in patients with relapsed radical operation using electron beam radiation therapy (IOERT), is a safe and effective therapy.

Martinez-Monge, since from January 1986 to June 1999, 67 patients were IOER
T treatment (including 36 cases of relapse cases and 31 cases of newly diagnosed cases). Not for the past history of radiotherapy for patients with preoperative radiotherapy and chemotherapy, or 45Gy irradiation, given cisplatin and 5-fluorouracil 1000mg/m2 20mg/m2 of chemotherapy. The primary case IOERT median dose 12Gy (10-25Gy); For relapse cases IOERT the median Gy dose (10-20Gy).

Results showed that all patients IOERT treatment of the 10 tumor control rate was 69.4%, primary and recurrent cervical cancer in 10 IOERT control rates were 92.8% and 46.4%. IOERT and found the tumor control rate and pregnancy marginal involvement (P = 0.001), residual tumor volume (P = 0.001) and pelvic lymph node involvement (P = 0.032) correlation. IOERT related toxicity total incidence was 14.9%, 8 patients (11.9%) patients with chronic pain, and 1 case (3.2%) patients with lower extremity motor neuropathy.

Researchers believe, but can be advanced surgical resection of cervical cancer patients is a valuable IOERT strengthening therapy, but by the Institute of IOERT dose for control of lymph node metastasis, parametrial invasion and (or) incomplete resection of the recurrent cancer, the effect is still poor.

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Tags: incidence, lymph, pain, patient, patients, radiation, radiotherapy, treatment

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