CERVICAL CANCER

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Squamous cell carcinoma
Cervical cancer squamous cell carcinoma to the main, about 90% to 95%, adenocarcinoma accounts for only 5% to 10%. But there no cancer in appearance SDT, and occurred in the Department of vaginal or cervical carotid tube.
(1) of the concept in the development of invasive cervical cancer, abnormal visual inspection of special, or similar general cervical erosion. With the emergence of invasive cervical cancer, cervical be in the following four types: 1. Erosive: around the cervix, mouth rough granular surface erosion, or irregular St. face, touched easy bleeding. 2. Exogenous: also known as hyperplasia or cauliflower-type. The polyp-like papillary or uplift, and then to the development of vaginal prominent ranging from the size of the cauliflower-like vegetation, focuses easy bleeding. 3. Within Type: also known as infiltration. Cervical cancer deep tissue infiltration, cervical and hard mast, but still smooth surface or only superficial ulcers. 4. Ulceration: whether endogenous or exogenous type of further development, the cancer tissue necrosis off, forming ulcers, or even for an entire cervical replaced by the empty, often due to secondary infections, there is a stench from the secretions. Cervical cancer is also particularly to the growth of the neck, cervical-barrel increase, which is within the A -
(2) check a mirror. Dysplasia: dysplasia performance for the bottom cell hyperplasia, the underlying cells not only proliferation, but also cells with nuclei and increasing disorder, with thick, uneven distribution of chromatin and nuclear heterogeneity change. Dysplasia can be divided into mild, moderate and severe. ① mild dysplasia (change as Level I): epithelial cells with slightly disordered, cells mild atypia, abnormal epithelial occupy one third of the cortex. ② moderate dysplasia (change as Ⅱ): epithelial cells with disorder, marked atypia, abnormal epithelial occupy two-thirds of the cortex. ③ severe atypical hyperplasia (change as Ⅲ): Almost all of epithelial polarity polar disorder or disappeared, significantly abnormal cell carcinoma in situ and have been difficult to distinguish.

2. DCIS: carcinoma in situ (CIS) also known as epithelial carcinoma. All of epithelial polarity disappeared, significantly abnormal cells, nuclear, with deep, uneven distribution of chromatin, mitotic rate. But the disease remains confined to the epithelium, no basement membrane penetration, seamless infiltration. Shaped along the cervical glandular cells can enter the transitional cavity openings with the cervical glands, resulting in the original column gland cells for multiple abnormal squamous cells alternative, but still maintain integrity of the basement membrane gland, a condition called cervical carcinoma in situ involving glands.

3. Under early invasive carcinoma: Endoscopic early invasive carcinoma in situ basis, occasionally there can be found in small cells have pierced the basement membrane, like the teardrop-shaped basement membrane into mesenchymal nearby, the depth of invasion less than 5mm, 7mm width not exceeding nor foci convergence phenomenon and no violations within the interstitial Vascular signs, without clinical features.

4. Squamous cell invasive carcinoma: When penetrate epithelial basement membrane cells, mesenchymal depth of more than 5mm, known as squamous cell invasive carcinoma. In between, there will be the quality of tree, of the cable of, or filled with the massive cancer nests.

According biopsy, cell differentiation can be divided into three: 1 Level I: differentiation good. Cancer nest in a considerable number of keratosis phenomenon clearly visible beads of cancer. ② Ⅱ: Medium division (up to the middle cervical cell differentiation), no significant cancer nest keratosis phenomenon. ③ Ⅲ: small cell undifferentiated (equivalent to the underlying cervical undifferentiated cells).

5. Adenocarcinoma: adenocarcinoma from the lining of the cervix and cervical surface of the columnar epithelium within the gland. Microscopically, the glandular structure can be seen, even with glandular cavity papillary processes. Epithelium proliferation is a multi-level, low cells, atypia obvious that mitotic phase. If cancer cells with adenovirus cavity, which can not find the original structure gland is often difficult to poorly differentiated adenocarcinoma and squamous cell carcinoma of the distinction. If both adenocarcinoma and squamous cell carcinoma of cervix, called adenovirus, squamous cell carcinoma. Gland, a high degree of malignant cancer, early metastasis, and poor prognosis.

Cervical intraepithelial neoplasia lesions
(1) cervical dysplasia
Mild dysplasia, cell atypia lighter, cell disorder with slightly; Obviously, moderate atypia, cell arrangement disorder; Severe significant abnormal cell polarity almost disappeared, and difficult to distinguish carcinoma in situ.
(2) cervical carcinoma in situ
Also known as epithelial carcinoma. Lesions to the cortex, basal membrane of penetration, mesenchymal no infiltration. Abnormal cells along the cervical glandular cavity openings in the transitional zone cervical glands, resulting in the original column gland cells for multiple <BR> replaced by abnormal squamous cells, but still maintain integrity of the basement membrane gland, known as cervical carcinoma in situ involving glands.
Cervical invasive carcinoma
Squamous cell carcinoma
About 90% to 95%. Squamous cell carcinoma and adenocarcinoma in appearance without special differences, the two are in the Department of vaginal or cervical carotid tube.
1. Giant seized cervical intraepithelial neoplasia lesions and early invasive carcinoma and under very early invasive carcinoma cervix, the naked eye observation no obvious abnormality, or similar cervical erosion, with the progressive development of the disease, has the following four types:
Exogenous (1): the most common. Lesions outward growth, also known as cauliflower-textured cauliflower. Organizations crisp, initially for the polyp-like papillary or uplift, and then to the development of vaginal prominent ranging from the size of the cauliflower-like vegetation, breach of easy bleeding.
(2) of the type: carcinoma of the cervix deep tissue infiltration, and the expansion of the uterine cervix under paragraph. Cervical mast while the hard, smooth surface and slight erosion, swelling of cervical cancer as a whole barrel.
3. Ulcer type: the two foci of the continued development of cancer tissue necrosis depression formed off ulcer or empty-shaped fiery Yamaguchi.
(4) type of neck: cervical cancer in the mouth, concealed in cervical, uterine cervix and into the next layer of blood and transferred to the pelvic lymph nodes, unlike endogenous type, which is special to the proliferation of invasive cervical and uterine segment of the blood and transferred to the pelvic lymph nodes, unlike Endogenous type, which is special to the proliferation of invasive cervical canal.
2. Microscopy
Under early invasive carcinoma (1): endoscopic see measurable lesions, interstitial infiltration of not more than five inches deep, horizontal spread of not more than seven inches, tumor infiltration by small lesions integration of different tumor cell differentiation.
(2) cervical invasive carcinoma: that mesenchymal tumor invasion has exceeded the scope of measurable early invasive carcinoma, or mesh with the massive integration Baptist mesenchymal weep. According to the generation of cells, generally fall into three: Level 1: better differentiation, cancer nests are in the majority were like keratosis, cancer-Visibility. Level II: moderate differentiation, the middle of cervical epithelial cell differentiation, cell sizes, cancer nest keratosis no obvious phenomenon. Ⅲ: mostly small cell undifferentiated (equivalent to the underlying cervical intraepithelial neoplasia undifferentiated cells).
Adenocarcinoma
About 5% to 10%.
1. Giant seized from the cervix, cervical wall infiltration. When the tumor longer than that process to a certain extent, I cervix, pregnancy often violated organizations. May was papillary cancer, bud-shaped, and supervising soup or infiltration. If the focus inward growth, cervical appearance can be completely normal, but parts of the cervical neck swelling like barrel.
2. Microscopy
Mucinous adenocarcinoma (1): The most common, from cervical mucus columnar cells, glandular structure microscope, cells containing mucus.
Cervical malignant adenomas (2): also known as the minimum deviation adenocarcinoma. Seemingly benign tumor cells, often invasive cervical wall deep.
3. Squamous carcinoma: cervical mucosa from columnar cells, and less see, naive cancer, adenocarcinoma and squamous cell carcinoma at the same time to develop in the direction of the father.

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Tags: bleeding, carcinoma, cell, early, erosion, infection, lesions, lymph, nodes, spread, vaginal, virus